The Comedy Central Roast of Rob Lowe took place over the holiday weekend. Comedian Nikki Glaser was there and she absolutely crushed Peyton Manning with a brilliant Tom Brady joke.

There was a clip circulating the information superhighway of Manning making a 'deflategate' joke, but it wasn't nearly as funny as what Nikki Glaser said. Here are a couple of tweets describing the joke:

and then for some reason, musician, Jewel chimes in:

It's almost as if Nikki Glaser was there defending Tom Brady's honor against Peyton Manning. Hilarious!